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26malik
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04/12/06 - 12:38 AM

A patient presents to a physician because of pain during defecation accompanied by blood in the stool. Physical examination demonstrates a large perianal mass.
Pathologic examination of the rectal mass following resection demonstrates a condyloma in which transformation to frank carcinoma has occurred. Which of the
following viruses would most likely be associated with these lesions?

A. Epstein-Barr virus (EBV)
B. Hepatitis B virus (HBV)
C. Human herpesvirus type 8 (HHV8)
D. Human papilloma virus (HPV)
E. Human T-cell leukemia virus (HTLV-1)

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vallia
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04/12/06 - 12:48 AM

D

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robin082006
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04/12/06 - 01:37 AM

D

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zaidsuror
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04/15/06 - 04:50 AM

D

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26malik
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04/17/06 - 06:58 AM

The correct answer is D.

The tumor is anal carcinoma arising in a condyloma. Both condyloma and anal carcinoma are related to human papilloma virus (HPV), which is also associated with cervical and penile condylomas and carcinomas.

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