| Author | 9 Posts |
pearljam59
Forum Guru
Topics: 120
Posts: 273
|
A 45-year-old man has a myocardial infarction. A coronary stent restores blood flow, but reperfusion causes a paradoxical increase in damage. Which of the following is the most likely mechanism of the new myocardial damage?
A) Direct poisoning of mitochondrial enzymes
B) Increase in lipid peroxidation of membranes
C) Inhibition of ATPase-dependent transport
D) Loss of intracellular amino acids
E) Prevention of cross-linking of labile amino acids
|
| yasmeen
Forum Guru
Topics: 70
Posts: 942
|
B DUE TO FREE RADICALS
|
| robin082006
Forum Hero
Topics: 471
Posts: 5,123
|
agree
___________________
The Key to Succeed is Patience.
|
| pearljam59
Forum Guru
Topics: 120
Posts: 273
|
Thats my thinking...free radicals! BUT don't free radicals ALSO cause an increase of mitochondrial permeability leading to release of enzymes?! That is why I am stuck between A and B.
I too chose B but then I started to overthink and overanalyze and now I cannot decide.
|
| dr_vetri
Forum Newbie
Topics: 4
Posts: 13
|
ans is B.reperfusion damage is due to free radicals.
|
| pearljam59
Forum Guru
Topics: 120
Posts: 273
|
Im still letting the records show that reperfusion ALSO causes increased permeability of mitochindria.
|
| Allison
Forum Senior
Topics: 20
Posts: 117
|
Answer B because superoxide radical production does damage of the cell mebrane.
|
| ssrpk
Forum Fanatic
Topics: 154
Posts: 2,819
|
hey, increase in mitochondrial permeability is due to lipid peroxidation of its membranes!
___________________
life is guud
|
| ManuNastai
|
B
|
|
| |
| | | | | | | | | |
You don't have permission to post.
|
