Prep for USMLEPrep for USMLE Forum
   Forum    Step 1  Step 2 CK Step 2 CS Step 3  Match  IMGs Resources Search






Previous Topic | Next Topic  NBME Form 2 ? 




 
Kaplan Qbank USMLE



Author7 Posts
  #1

Picture shows structure of acetaminophen with OH as the side chain on one side and this OH side chain gets converted to O3SO in a particular reaction. Which of the following metabolic processes share the same metabolic pathway as that reaction?

a) deamination of deamphetamine
b) formation of minoxidil sulphate
c) hydrolysis of acetyl salicylic acid
d) N-dealkylation of deipramine
e) N-hydroxylation of meperidine

shocked

Attached Files:
Acetaminophen.gif (1 KB, 83 downloads)
attachment
  #2

rolling eyes no idea.... anyone

  #3

sounds like a Doctor of Pharmacology q. Id guess e.

___________________
Smell the coffee! "Is That an Osler move??"

  #4

i would choose B. the reaction is sulphation (SO3).

___________________
It has been a looooong hard journey but I am inches away from my destination...

  #5

B, I just guess that.

This seem to be an reaction to change toxic metabolic of acetaminophen to non-toxic metabolic.

N-Acetyl Cysteine is used in cases of Acetaminophen intoxication in order to give sulphur group for the detoxication, so I guess B.




___________________
The Key to Succeed is Patience.

  #6

minoxidil must be sulfated to be active...so i'd go for B too.

  #7

So what is the correct answer?








You don't have permission to post.




Login or Register to post messages in this topic





















Contact | Leaders | Disclaimer | Privacy

Copyright @ Prep for USMLE. All rights reserved.