pearljam59
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A 55 year old man with diabetes mellitus has burning dysesthesias over the lateral aspect of his left lower leg. Capsaicin - containing cream is effective in alleviating the symptoms. The substance most likely to have caused the dysesthesias is
a) ADH (vasopressin)
b) angiotensin II
c) dopamine
d) inositol
e) neuropeptide Y
f) nitric oxide
g) norepinephrine
h) substance P
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| gogetit
Forum Senior
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substance p
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| yasmeen
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AGREE
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| mjl1717
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substance p is the only substrate there that has anything to do with pain. NO2 is known for dilating and in a scheme with guanosine used for erectile dysfunction. Also dopamine beta hydroxlase aids catecholamine dopamine to get N.E. ADH should come into play with volume depletion or increase osmolarity. Inositol is a proposed mecn of action for Lithium. neuropeptide Y??
Edited by mjl1717 on 04/04/06 - 12:06 PM
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| pearljam59
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Let me tell you...if you get to USMLE and you see a question with answers A-J DONT GET INTIMIDATED. Through my practive with NBME it is always an easy answer choice but they try to throw as many answers out to slow you down and say "Oh wait, I am not sure what this answer does so MAYBE it is the one!"
Blasphemy.
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| robin082006
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Good point pearljam59
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| mjl1717
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anyone know what neuropeptide y is used for?
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