dr_vetri
Forum Newbie
Topics: 4
Posts: 13
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hi,
iam reading kaplan notes for path and its given, there is p-ANCA association with polyarteritis nodosa.
robbins says that there is no association and p-NCA is associated with microscopic polyangitis and churg strauss..
help me regarding the correct answer!
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| p53
Forum Guru
Topics: 51
Posts: 804
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Nothing is more authoritative for pathology than 'Robbins'!
by the way, Goljan also says (incorrectly) that there is p-ANCA association with polyarteritis nodosa.
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"Everything should be made as simple as possible, but not simpler." - Albert Einstein
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| sosikan
Forum Junior
Topics: 3
Posts: 78
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p anca doesnt associated with pan
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| general malaise
Forum Guru
Topics: 14
Posts: 433
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i've had this doubt for a while, every source but robbins says PAN is associated with p-anca. i trust robbins over every thing else but i wonder what the boards thinks on it.
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"El respeto al derecho ajeno es la paz" Benito Juarez
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| p53
Forum Guru
Topics: 51
Posts: 804
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OK, I'll check in clinical textbooks.
Board thinks what is reality and reality can be only one - either PAN is associated with p-anca or not.
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"Everything should be made as simple as possible, but not simpler." - Albert Einstein
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| nida
Forum Elite
Topics: 23
Posts: 87
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Laboratory Findings
Most patients with polyarteritis nodosa have a slight anemia, and leukocytosis is common. The ESR is often (but not always) strikingly elevated but, in general, serologic tests—particularly autoantibodies—are of little help in making the diagnosis. Patients with classic polyarteritis nodosa are ANCA-negative and may have low titers of rheumatoid factor or antinuclear antibodies, both of which are nonspecific findings. In patients with polyarteritis nodosa, appropriate serologic tests for active hepatitis B infection must be performed.
From Harrison online
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| dr_sarim
Forum Senior
Topics: 16
Posts: 75
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guys..i guess there shouldnt be much debate on P-ANCA being +ve in PAN ...its only 30% cases so -ve test does not exclude the dx..secondly BANG!!! both p-ANCA and C-ANCA can be +ve in PAN (source: emedicine.com) ...so i think we shouldnt make much fuss about this ...i would follow kaplan and brs in this matter
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| dr_neonatology
Forum Senior
Topics: 11
Posts: 66
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Goljan said the p-ANCA is associated with PAN.
Best regards
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