50. A 54-year-old man is brought to the emergency department because of a 2-week history of progressive shortness of breath with exertion and leg swelling. He now requires two pillows for sleeping because of shortness of breath when lying flat. He has had a 4.5-kg (10-lb) weight gain during this period. He has a 15-year history of type 2 diabetes mellitus and hypertension that are poorly controlled despite treatment with a variety of medications. Two months age, he began receiving a new diabetic medication that has been titrated upward during the past month. Crackles are heard at the lung bases bilaterally. Cardiac examination shows and S3 gallop. There is 2+ peripheral edema of the lower extremities. Which of the following medications is the most likely cause of the new symptoms in this patient?
A) Acarbose B) Glyburide C) Metformin D) Repaglinide E) Rosiglitazone
yasmeen Forum Guru
Topics: 67 Posts: 936
03/30/06 - 01:41 PM  
 
   
 
  #2
E BUT
huzefa Forum Junior
Topics: 2 Posts: 66
03/30/06 - 01:59 PM  
 
   
 
  #3
E. One of the side effects of Rosiglatizone is Fluid retention with weight gain. Hard question.
selsibeel Forum Newbie
Topics: 1 Posts: 10
09/24/06 - 09:59 PM  
 
   
 
  #4
Thank you
klimt Forum Guru
Topics: 27 Posts: 605
10/01/06 - 09:43 AM  
 
   
 
  #5
didn't know that. So Rosiglatizone produces CHF?! ___________________ Traveler, there are no roads. Roads are made by walking.
prasanthtalluri Forum Newbie
Topics: 0 Posts: 2
10/04/06 - 09:29 PM  
 
   
 
  #6
klimt wrote: didn't know that. So Rosiglatizone produces CHF?!
probably answer is B AS THE SULPHONYLUREAS cause the weight gain and edema.not the glitazones.these have the potency of toxicity on liver