mutation

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Prep4USMLE Forum » USMLE Step 1 Forum » Histology & Molecular Biology

mutation

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2 Posts

leen
Forum Guru

Topics: 79
Posts: 294

03/30/06 - 11:30 AM

wat is the diff between splice donor n splice acceptor mutation?

thanks

ManuNastai
Transilvanian..
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Topics: 55
Posts: 838

04/04/06 - 12:03 PM

I think ou know what splicing is.

donor: durring splicing, the final product mRNA is shorter than it should be du to a loss of one or more exons (and maybe parts of exons ?!)

acceptor: the mRNA is longer due to a defect in the excisio of introns. it my cantain whole or parts of introns which are not recognized as introns and are translated into defective, longer proteins

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