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Kaplan Qbank USMLE



Author10 Posts
  #1

A 72-year-old man comes to the emergency department because of a 2-hour episode of loss of vision in the leR eye. He has never smoked.

Laboratoty studies show:

Hemoglobin 20 g/dL
Hematocrit 62%
Leukocyte count 14,200/mm3
Differential normal
Mean corpuscular volume 87.2 /m3
Platelet count 375,000/mm3

Which of the following is the most appropriate initial therapy?

A) Admlnlstratlon of allopurlnol
B) Administration of asoirin
C) Administration of chiorambucil
D) Administration of hydrowurea
E) Admlnlstratlon of warfarin
F) Phlebotomy
G) Splenectomy

shocked

  #2

ok its polycythemia rubravera so its either f or d but i,m inclined towards f.

  #3

F

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  #4

F.

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  #5

Agree with F, but who will post the correct answer?


  #6

no one can post official answer, it's on nbme form, but if it looks like f, and seems like f, then most likely it's... F nod

Edited by hottie99 on 04/04/08 - 10:59 PM

  #7

Ok I want to be really sure why we are not using Aspirin. Is it the normal platelet count (N = 150,000-400,000)?


  #8

yeah i did the same mistake when i took the nbme, i thought he had a stroke, so i put give ASA, but his hematocrit is off the charts, indicating polycythemia, and the treatment for that is phlebotomy. ASA wont decrease it that fast as will phlebotomy, and yes his platelets are within normal range, we're treating to reduce hct, not the platelet count

  #9

But what should be the answer if he had both an increased Hct and an increased platelet count?


  #10

hi
asa will not decrease platelet count ,it will only cause functional platelet dysfunction.
Merely increased platelet count does not cause aggregation of platelets .. if there is a platelet plug/thrombus over there ,it will be formed due to an initial injury to endothelium / activation of coagulation . In that case , there would be a thrombus even if the platelet count was normal.
phlebotomy will treat both increased platelet count and erythocyte count

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