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Previous Topic | Next Topic  Spleen: open and closed circulation 




 
Kaplan Qbank USMLE



Author7 Posts
  #1

Could someone kindly explain the difference between open and closed circulation in spleen?

thank you.

  #2

anyone??

  #3

raised eyebrowshockedshaking head

will look it up and re;ly if i understand it...


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  #4

In closed circulation through the spleen, blood empties from the vessels of the white pulp into sheathed capillaries of the red pulp and then directly into the sinuses.
• In open circulation, blood empties from the sheathed capillaries into the splenic cords and then enters the sinuses through slits in the wall.

  #5

- Does the spleen have closed or open circulation? - It is not completely known.
Open = terminal arterial capillaries open into pulp reticulum and blood
gradually filters into venous capillaries (sinusoids)
Closed = arterial capillaries enter directly into venous sinuses, but capillaries
with large hole (discontinuous capillaries) so RBCs can be exchanged freely
- It appears that open circulation predominates and that closed circulation serves only a
minor role.

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  #6

1Trabecular veins
2Trabecular arteries
3Pulp veins
4Penicillar arterioles
5Follicle with follicle capillaries
6Artery with periarterial lymphatic sheath (PALS)
7Splenic sinus
8Reticular fibrous framework
9Open capillaries
10 closed capillaries.

  #7

this topic is still not clear and wel-explained in the scientific literature







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