leen
Forum Guru
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After taking an overdose of propranolol, a 35 yr old woman developes sinus bradycardia and syncope. In order to stimulate the same second messenger system that is activated by ¦Â-adrenergic receptors, which of the following drugs will be most effective to increase her heart rate?
A. ADH (Vasopressin)
B. Atrial Natriuretic peptide
C. Clonidine
D. Glucagon
E. Phenylephrine
taken from other forum ...so dont know the right ans 
pl help in solving it...
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| lalitha
Forum Junior
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positive inotropic and chronotropic , not via activation of beta1 , but through glucagon receptors that are G - protein linked to adenylyl cyclase . so it is used in beta blocker overdose.
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| star1
Forum Guru
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Correct heart tissue has glucagon receptor i read some where but cant remember . plz tell me ??
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| lalitha
Forum Junior
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it is in kaplan notes endocrinology(pharma)
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| star1
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Thanks lalitha
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| Cedrick
Esculapio
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Nice,I did not know this
Glucagon
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| robin082006
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D
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| Diego Casali
Forum Elite
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D
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| pocas
Forum Elite
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YES for b block overdose is GLUCAGON .
PHENILEFRINE is alpha agonist , so it increase the blood pressure not the heart rate
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| mjl1717
Forum Hero
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the heart is beta an ONLY BETA, , phenylephrine could cause a reflex brady cardia but glucagon is correct.
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| vamsi2004
Forum Elite
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aisha,, alpha 1 works thur PIP2 system, not alpha 2
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