vickimed
Forum Newbie
Topics: 5
Posts: 8
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Boys and girls:
NBME Questions need answer:
1. A 23 yr old man who recently emigrated from Costa Rica is admitted to the emergency department with seizures. Finding on examination of his cerebrospinal fluid are within the reference range. A CT scan of the head shows numerous cortical lesions with calcifications; some have surrounding edema. The life cycle of the parasite causing these lesions involves:
A. The bite of a blackfly to human
B. The bite of a mosquito to human
C. The bite of a sandfly to human
D. Passage through cows
E. Passage through pigs
2. A 35 yr-old man who takes street drugs intravenously develops fever, cough, and hemoptysis. X-ray file of the chest shows bilateral infiltrates. Echocardiogram discloses a 1-cm mass that is attached to the tricuspid valve. Blood culture grows yeast. The most likely causal organism is:
A. Aspergillus flavus
B. Candida Albicans
C. Cryptococcus Neoformans
D. Histoplasma Capsulatum
E. Mucor Species
3. Latent infection with which of the following viruses is associated with expression of some (but not all) viral genes in B lymphocytes?
A. Epstein-Barr virus
B. Hepatitis B Virus
C. Measles Virus
D. Simian Virus 40
E. Varicella-zoster Virus
4. After a full course of immunization with a new vaccine consisting of a recombinant polypeptide, 10% of adults fail to make antibody to the polypeptide. The nonresponders have an increased frequency of one HLA type. What is the most likely explanation for the failure of this group to respond to immunization?
A. Failure of B lymphocytes to recognize the polypeptide
B. Failure of T lymphocytes to recognize the polypeptide
C. Lack of Class I MHC Presentation of the polypeptide
D. Lack of Class II MHC Presentation of the polypeptide
Thanks
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| skyhigh
Forum Guru
Topics: 105
Posts: 561
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i think E, B, E, D
Not sure about 3
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| vickimed
Forum Newbie
Topics: 5
Posts: 8
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Thanks again, skyhigh
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| robin082006
Forum Hero
Topics: 471
Posts: 5,125
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1. E (Taenia solium or pork tapeworm)
2. B
3. E (Shingles)
4. D (but not sure about other choices)
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| mazinger
Forum Guru
Topics: 46
Posts: 917
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dont agree with you guys in number 3, why? because VZV belongs to alpha family of herpesviridae. I dont think it has tropism for this kind of cells, the one that can replicate in b lymphocites is EBV, which belongs to gamma family or subtype. Well, what do you think? do you agree? if not, give answers why not..
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| yasmeen
Forum Guru
Topics: 67
Posts: 936
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i agree with u .ebv has latent phase in b lymphocytes
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| Cedrick
Forum Fanatic
Topics: 320
Posts: 1,928
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1.- E.-Pigs
2.- B.-Candida albicans
3.-A.-EBV
4.-D.-lack of class II MHC
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