leen
Forum Guru
Topics: 79
Posts: 294
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500 mg doseof a drug has therapuetic efficacy for 6 hrs .If the half life of the the drug is 8 hrs ,for how long a 1 mg dose be effective?
1. 8 hours
2. 12 hours
3. 14 hours
4. 16 hours
5. 24 hours
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| doc179
Forum Guru
Topics: 67
Posts: 1,217
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14 hrs
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| leen
Forum Guru
Topics: 79
Posts: 294
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can pl explain how u calculated it?
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| doc179
Forum Guru
Topics: 67
Posts: 1,217
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When 1000 mg is given, 500 mg is left after 8 hrs since t1/2=8 hrs.
Then that 500 mg is effective for another 6 hrs (given).
So if 1000 mg was administered, you get the therapeutic effect for 8+6=14 hrs.
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| leen
Forum Guru
Topics: 79
Posts: 294
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thanks
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