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Kaplan Qbank USMLE



Author8 Posts
  #1

A 20-year-old woman receives allergy shots to control her seasonal allergy to pollens. The rationale for the therapy is desensitization by stimulation of production of allergen-specific antibodies of which of the following classes? Click on the circle next to your answer choice
A. IgA
B. IgD
C. IgE
D. IgG
E. IgM




  #2

My first choice WAS IgA, I think you want to make her produce enough antibodies in order for the allergen be unable to reach IgE at mast cells.. ow that I think of it a person cannot develope IgA through shots.. So its got to be IgG. What's the answer? Im getting confused.

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original mazinger z

  #3

yeah quite confusing ..I think I will also go for IgG...but will definitely wait for the correct answer

  #4

but initial response is IgM isn't it? i would have chosen E.

  #5

the correct answer is IgG. Dear mazinger you are in the right way. Can you plz explain it more, I don't know anything about such a treatment and what exactly is its mechanism??

  #6

ok you guys are right it has to be IgG cause what we want to achieve is a long-lasting immune response.
the treatment is as far as i have understood like this: patient is exposed to very small doses of allergen, then with time allergen dose is slowly increased so that immune system "can get used to it".

  #7

the pt is allergic to pollens which will be mediated by IgE ...so to desensitize her the shots are given which would increase specific IgG levels in the blood and those would bind to the antigen when exposed leaving none for IgE and hence no allergy...this is what I think

  #8

Sorry on the late response, but doc179 is right..

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original mazinger z







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