ManuNastai
Transilvanian..
Topics: 55
Posts: 838
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I read the Neoplasia from Robbin's Pathology.
I know everybody knows about p53 oncogene and about Rb (expecially from Goljan's Path), but do we have to know all those other genes (sis, mad, max etc)? I mean, do we have to know their mechanism of action and in what tumors there are mutations in those genes?
Thank you
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"Love is the only inflamation of the heart that drains in the vagina" (translation after Dr Petre Florescu, Professor of Pathology, UMF "Iuliu Hatieganu", Cluj Napoca
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| p53
Forum Guru
Topics: 51
Posts: 804
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these questions are appearing more and more frequently on the step 1 - you should know not only their mechanisms of action and in the development of which tumors they are implicated, but also concrete mutations leading to the inactivation of antioncogenes, or activation of oncogenes, i.e. on which chromosomes they are located.
by the way, p53 isn't oncogene, it's antioncogene.
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"Everything should be made as simple as possible, but not simpler." - Albert Einstein
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| ManuNastai
Transilvanian..
Topics: 55
Posts: 838
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thanks for the response and for correcting me, even if it is a very upsating news for me
___________________
"Love is the only inflamation of the heart that drains in the vagina" (translation after Dr Petre Florescu, Professor of Pathology, UMF "Iuliu Hatieganu", Cluj Napoca
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