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doc179
Forum Guru

Topics: 67
Posts: 1,217
03/07/06 - 11:54 PM             #1

) Antimicrobial factors that are products of secretory glands include which of the following molecules?
A)IFN gamma
B)Lacto peroxidase
C)Lysosomes
D)Arachadonic acid
E)Aryl sulfatase

doc179
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Topics: 67
Posts: 1,217
03/08/06 - 12:00 AM             #2

A 14-year-old boy develops a pruritic vesicular rash on his face and hands 3 days after hiking in the woods. Which of the following are most likely to be involved in his illness?

A)Antibody, complement C5-9

B)Circulating immune complexes; complement C5a, neutrophils

C)Cytotoxic T lymphocytes

D)IgE, mast cells, histamine, cytokines

E) Lymphocytes, cytokines, macrophages


sturge_weber
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Topics: 77
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03/08/06 - 01:05 AM             #3

is it e, for the second q, delayed type hypersensitivity

for the first one is c lysosomes or lysozyme


enthu
Forum Junior

Topics: 14
Posts: 42
03/08/06 - 01:18 AM             #4

the second quest..its rocky mountain spotted fever....does it produce typ 4 hypersensitivity?...can u explain aa bit sturge weber..thanks

doc179
Forum Guru

Topics: 67
Posts: 1,217
03/08/06 - 03:40 AM             #5

I got these Qs from some other forum so I am not very sure abt the Qs and answers whether they are correct..sorry abt that but after going thru the choices even I thought that for the first one it should be lysozyme instead of lysosome but is it not lysozyme which is secreted by the glands...? I can not think of any other choice as the answer as aryl sulfatase is released by the eosinophil and abt the 2nd Q I thought its contact dermatitis and not rocky mountain fever as in the latter the rash is petechial and not vesicular and if I am correct then it should be E but a little confused abt option C though I know that the ans Esad...could you pls explain sturge weber..thanx

r_albayunen
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Posts: 218
04/12/06 - 11:01 PM             #6

number 1 im confused .. i thought c
number 2: contact dermatitis .. its a cell mediated type IV HSR .. its does has vesicular lesions with a rash and pruritus .. im just confused with the onset of symptoms and signs .. i think 3 days is too late .. but i still think C

paganini
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Topics: 26
Posts: 153
04/13/06 - 12:48 PM             #7

I think that the most correct answer is E. Is a contact dermititis maybe to poison ivy(cathecol), this plant grows wild in USA woods. Type IV hypersensitivity is directed by cytokines released by TH1 cells stimulated by antigen. Antigen is processed by tissue macrophages (in this case Langerhan's cells in the skin) and stimulates TH1 cells. Lipid-like haptens like cathecol in poison ivy can diffuse through the plasma membrane and bind intracellular proteins, this haptenated proteins are delivered to the cell surface associated with MHC I molecules so can activate cytotoxic CD8 cells. dermatitis is mediated by CD8 T cells. The delay in the appearance of a type IV hype sensitivity reaction is due to the time it takes to recruit antigen-specific T cells and other cells to the site of antigen localization and to develop the inflammatory response. In conclusion you need not only lymphocytes but also macrophages and the cytokines. Dimelo TONIN! smiling face

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paganini
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04/13/06 - 12:48 PM             #8

I think that the most correct answer is E. Is a contact dermititis maybe to poison ivy(cathecol), this plant grows wild in USA woods. Type IV hypersensitivity is directed by cytokines released by TH1 cells stimulated by antigen. Antigen is processed by tissue macrophages (in this case Langerhan's cells in the skin) and stimulates TH1 cells. Lipid-like haptens like cathecol in poison ivy can diffuse through the plasma membrane and bind intracellular proteins, this haptenated proteins are delivered to the cell surface associated with MHC I molecules so can activate cytotoxic CD8 cells. dermatitis is mediated by CD8 T cells. The delay in the appearance of a type IV hype sensitivity reaction is due to the time it takes to recruit antigen-specific T cells and other cells to the site of antigen localization and to develop the inflammatory response. In conclusion you need not only lymphocytes but also macrophages and the cytokines. Dimelo TONIN! smiling face

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Mr. Physiology. An answering machine.

cool_guyp4u
Forum Elite
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Topics: 12
Posts: 124
04/19/06 - 01:04 PM             #9

doc179 wrote:
A 14-year-old boy develops a pruritic vesicular rash on his face and hands 3 days after hiking in the woods. Which of the following are most likely to be involved in his illness?

A)Antibody, complement C5-9

B)Circulating immune complexes; complement C5a, neutrophils

C)Cytotoxic T lymphocytes

D)IgE, mast cells, histamine, cytokines

E) Lymphocytes, cytokines, macrophages



The Q has inadequate details. the author in the other forum was hiding the whole Q? I bet the exam wouldn't post such Qs.


doc179
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Topics: 67
Posts: 1,217
04/19/06 - 02:00 PM             #10

well...I found these Qs in someother forum and I have copied everything abt this Q I could find in that forum.







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