USMLEGladiator
ck, CS Finish by Feb09
Topics: 126
Posts: 587
|
6. A 75-year-old woman with metastatic small cell carcinoma of the lung is brought to the emergency department after collapsing. On arrival, she is pale, sweating, and lethargic. Her temperature is 37.2°C (99°F), pulse is 130/min and weak, respirations are 25/min, and blood pressure is 90/60 mm Hg. Breath sounds are decreased bilaterally. An x-ray of the chest shows a tumor mass in the hilar area and an additional radiodensity in the left lower lobe of the lung. She dies within a few hours despite supportive care and antimicrobial therapy. Cultures of blood collected at the time of admission grow Klebsiella pneumoniae. Which of the following is the most likely mediator released from macrophages that initiated the process that led to her death?
A. Alpha-1-Antitrypsin
B. Complement C3b
C. C-reactive protein
D. Factor XII (Hageman factor)
E. Interferon-gamma
F. Interleukin-8 (IL-8)
G. Platelet-activating factor
H. Tumor necrosis factor
I. Interferon-alpha
WHAT IS ANS & DIAGNOSIS.
___________________
Be confident,do hard work,forget past failures and success is yours.......
|
| mix
Forum Newbie
Topics: 0
Posts: 1
|
h????
|
| robin082006
Forum Hero
Topics: 471
Posts: 5,125
|
Sound like sepsis
I go with H too
___________________
The Key to Succeed is Patience.
|
| vinaysaini19
Forum Junior
Topics: 15
Posts: 64
|
Yes h, may be not sepsis but lobar pneumonia of secondary type.
|
| sosikan
Forum Junior
Topics: 3
Posts: 78
|
tnf is the right answer.cause tnf and ıl 1 is secreted by makrofaj when an infection happens
|
| twesting2173
Forum Senior
Topics: 7
Posts: 65
|
i think you might get increased breath sounds wiht a pneumonia
|
| young_doc
Forum Guru
Topics: 55
Posts: 732
|
This is a simple conceptual question. Do not be intimidated by the size of the stem!
Macrophages only secrete 2 cytokines, IL-1, and TNF-alpha.
So even if you knew nothing else about neoplasms, infections, etc....the answer was still clear!
___________________
First Aid is my Bible...
|
| antidepressant
Forum Guru
Topics: 33
Posts: 764
|
i picked H too, nice trick.
___________________
Step 1 can not defeat me!!!!!!!!
|
|
| |
| | | | | | | | |
