malinda
Forum Guru
Topics: 162
Posts: 654
|
A 15-year-old white male presents with a hemarthrosis of the right knee joint and a recent history of protracted
bleeding from cuts or scrapes. He has no family history of bleeding disorders. The patient also notes a long
history of chronic abdominal discomfort and diarrhea, which has been worse for the last 6 months, occasionally
accompanied by fever. Physical examination reveals a patient at the 5th percentile for both height and weight; an
actively bleeding rectal fissure is also noted. Both prothrombin time and the partial thromboplastin time are
prolonged. Laboratory evaluation of the blood is likely to reveal low levels of
A. factor VIII
B. factor IX
C. factors II, VII, IX, and X
D. factors II, V, VII, IX, and X
E. von Willebrand's factor
___________________
I CAN DO IT.
|
| mazinger
Forum Guru
Topics: 46
Posts: 918
|
e
___________________
original mazinger z
|
| malinda
Forum Guru
Topics: 162
Posts: 654
|
in that case there will be prolonged ptt prolonged bleeding time but normal PT.
___________________
I CAN DO IT.
|
| general malaise
Forum Guru
Topics: 14
Posts: 433
|
C...malabsorption of vita K
___________________
"El respeto al derecho ajeno es la paz" Benito Juarez
|
| malinda
Forum Guru
Topics: 162
Posts: 654
|
correct.But why is the answer not D?both have elevatd PT and PTT,
___________________
I CAN DO IT.
|
| general malaise
Forum Guru
Topics: 14
Posts: 433
|
vitamin K needed for carboxilation glutamyl residues of factors II, VII, XI, X, protein C
___________________
"El respeto al derecho ajeno es la paz" Benito Juarez
|
| general malaise
Forum Guru
Topics: 14
Posts: 433
|
malinda...may i ask what study sources you are using for path?
___________________
"El respeto al derecho ajeno es la paz" Benito Juarez
|
| malinda
Forum Guru
Topics: 162
Posts: 654
|
I am all confused here guys.Vit K dependent factor deficincy..doesnt it affect PT only as warfarin does.so why is that PTT also elevated in this pt?
___________________
I CAN DO IT.
|
| malinda
Forum Guru
Topics: 162
Posts: 654
|
I am using kaplan and goljan.
___________________
I CAN DO IT.
|
| robin082006
Forum Hero
Topics: 471
Posts: 5,125
|
C because of Vit K deficiency
___________________
The Key to Succeed is Patience.
|
| druas
Forum Elite
Topics: 47
Posts: 322
|
C..
|
| druas
Forum Elite
Topics: 47
Posts: 322
|
i think b/c factor 2 and 10 are both required for final common pathway of both intrinsic and extrinsic systems....therefore elevated PTT and Pt...thats my thought
|
| general malaise
Forum Guru
Topics: 14
Posts: 433
|
PT measures factor VII, and PTT measures the rest. they share common final pathways which is why both PT and PTT will be prolonged
___________________
"El respeto al derecho ajeno es la paz" Benito Juarez
|
| malinda
Forum Guru
Topics: 162
Posts: 654
|
oh I get it...thanx
___________________
I CAN DO IT.
|
| mazinger
Forum Guru
Topics: 46
Posts: 918
|
agree with your explanation.. its vit k deficiency
___________________
original mazinger z
|
|
| |
| | | | | | | | | | | | | | | |
