DrVirgo
Forum Hero
Topics: 1055
Posts: 3,377
|
35. A 50-year-old man who has had a myocardial infarct was subsequently diagnosed as having familial hypercholesterolemia, an autosomal dominant disorder. His son has not been tested for hypercholesterolemia. What is the probability that the patient's granddaughter, through his son, will have hypercholesterolemia?
A ) Less than 1%
B ) 10%
C ) 25%
D ) 33%
E ) 50%
Please explain your answer. ty.
___________________
Our greatest glory is not in never falling, but in rising every time we fall.
|
| robin082006
Forum Hero
Topics: 471
Posts: 5,125
|
C. 25%
His son has 1/2 chance of disease
His son's daughter inherits 50% gens from his son
Therefore, his granddaughter's chance is 1/2*1/2=1/4=25%
___________________
The Key to Succeed is Patience.
|
| DrVirgo
Forum Hero
Topics: 1055
Posts: 3,377
|
I agree...
We share 1/4 of our genes with our grandparents... correct?
___________________
Our greatest glory is not in never falling, but in rising every time we fall.
|
| sturge_weber
Forum Guru
Topics: 77
Posts: 1,042
|
ya , we give 50% of our genes to offsprings, so it will be 25%
|
| agarow
Forum Newbie
Topics: 1
Posts: 4
|
Sorry guys, I did not get the answer.
can you break id down?
|
| ManuNastai
Transilvanian..
Topics: 55
Posts: 838
|
Hi!
Because that guy had MI at the age of 50, he is surelya heterozygote. Therefore he is Xx. We take the situation in which his wife is not carrying the disease . So, their son has a 50% probability of being Heterozygote (ill) and 50% prob of being a well homozygote.
Lateron, the son's daughter has the same 50% prob of being a ill heterozygote. But we're asked what is the prob that if the GRANDFATHER has it, to pass it to the grandaughter which is 0,5*0,5=0,25
___________________
"Love is the only inflamation of the heart that drains in the vagina" (translation after Dr Petre Florescu, Professor of Pathology, UMF "Iuliu Hatieganu", Cluj Napoca
|
| Cedrick
Forum Fanatic
Topics: 320
Posts: 1,928
|
oh ok
|
|
| |
| | | | | | | |
