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Kaplan Qbank USMLE



Author13 Posts
  #1

22. Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) protein alter which of the following ion transport mechanisms?


A) Ca2+-activated Cl– secretion



B) Ca2+-activated Cl– uptake



C) Cyclic AMP (cAMP)-stimulated Cl– secretion



D) cAMP-stimulated Na+ secretion



E) cAMP-stimulated Na+ uptake


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  #2

B??

  #3

Id guess B also

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  #4

I go with C


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  #5

C is the ans

  #6

anyone know the answer for sure? source?

___________________
Our greatest glory is not in never falling, but in rising every time we fall.

  #7

ya i would also go for c...

  #8

Can you all please explain WHY you think B or C is right?
thanks. smiling face
-Also, why is it NOT choice A?

___________________
Our greatest glory is not in never falling, but in rising every time we fall.

  #9

I did a search for the mechanism of the chloride channel function here ...the channel that is involved in cystic fibrosis acts via cAMP...I do not know how to explain this...

  #10

Oh, ok... So it it linked with G Protein S which stimulates cAMP?


___________________
Our greatest glory is not in never falling, but in rising every time we fall.

  #11

looks like that as it was not in much detail and I know only Gs which increases cAMP

  #12

The answer is c.
i read this question in kaplan qbank i think

  #13

the answer is C.REFERENCE IS HARPER.







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