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Kaplan Qbank USMLE



Author6 Posts
  #1

a mother has waardenburg syndrome{AD}her husband is unaffected and they plan to have a family with three children.what is the probability that one of the three children will be affected?
A.1/8
B.1/4
C.3/8
D.1/3
E.7/8

AND Family with father ,grandfather and grandmother suffering from gardner's syndrome.father has 4 children.what are the chances that atleast one child has inherited the gardner's syndrome allele?
A.1/4
B.1/2
C.3/4
D.13/16
E.15/16

PLEASE explain your answer


  #2

the ans for the first Q seems like c. The possibility that a child will be affected is exactly the same as it being unaffected. I think I did it the hard way, by writing out all possibilities. If A is affected and X is not affected, the possibilities are:

AAA
XAA
AXA
AAX
XXA
XAX
AXX
XXX

Eight possibilities. According to this, the chance of

All children being affected is 1/8
One child being affected is 3/8
Two children being affected is 3/8
All children being affected 1/8.

The answer is C if the question means what is the probability of EXACTLY one child being affected. The probability of ATLEAST one child being affected is 7/8 (E).

Now I need someone to help me interpret this question right. Exactly one child or atleast one child?

Will post for the second part later, if I can..........

  #3

1/2+1/2+1/2 = 3/8???

32/16 = 1/2 ???

  #4

Thats exactly what i was saying....thats how wrong i am disapproval

My maths is As terrible as my medicine.


Edited by sarika on 02/21/06 - 12:05 AM

  #5

because AD, every child has 1/2 chance to have disease and 1/2 chance normal.

so we think about coin tossing

for the first question, doc179 is right, ans is 3/8

for the second question, ans is E. 15/16

Gardner is AD disease, each child has 1/2 chance to have disease, the probability that all 4 children are normal is 1/2*1/2*1/2*1/2= 1/16, so the probability that at least one child has disease is 1-1/6= 15/16.


___________________
The Key to Succeed is Patience.

  #6

more explanation about the second question

all 4 children are normal = 1/16

exactly 1 child with disease = 4/16

exactly 2 children with disease = 6/16

exactly 3 children with disease = 4/16

all 4 children with disases = 1/16


___________________
The Key to Succeed is Patience.







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