DrVirgo
Forum Hero
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According to Kaplan, during Iodine deficiency, the thyroid produces more T3 than T4 (normally T4 is more abundant)...
Anyone know why this is?
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| chazan
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T4 is made with coupling of 2 diiodotyrosines
T3 is made with coupling of 1 di-iodotyrosine and 1 MONO-iodotyrosine.
So in Iodine deficiency, the body just makes more T3 b/c it requires one less iodine.
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| DrVirgo
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Ok, so since there is an iodine deficiency, there will be more MIT made than DIT, so more likely for MIT and DIT to pair making T3?
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