DrVirgo
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4. A protein contains a 30-amino acid structural motif with four cysteine residues coordinated to a zinc atom. In which of the following is this structured motif most likely to be found?
A) Nucleosome
B) Ribonuclease
C) Ribosome
D) Spliceosome
E) Transcription factor
17. Phenylketonuria is an AR autosomal recessive disease. What is the probability that the asymptomatic brother or sister of a child with the disease is a heterozygous carrier?
A) 0
B) 1/4
C) 1/2
D) 2/3
E) ¾
explain answers. thank you.
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| sarika
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17, D 2/3
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| endocrine
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4E?,17d
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| nadiabarati
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4. B
17. D
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| DrVirgo
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4. What is the structure being described?
17. Please explain the answer.
thanks.
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| robin082006
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4. Zinc atom (hint)--> transcription factor
17. 2/3
the child has ds--> both parent must be heterozygous.
The brother or sister of the child has 2/4 chance to be heterozygous. Because they are asymptomatic, we exclude anormal homozygote (aa), therefore their chance of heterozygote is 2/3.
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| msyamp
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robin has got it
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| vinaysaini19
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What is Biochem NBME. I think its the Biochemistry ques. appearing in NBME practise exams. Is it?
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| vamsi2004
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unable to understand q17. can someone plz explain..
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| Musuq
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the qst says "What is the probability that the asymptomatic brother or sister of a child with the disease is a heterozygous carrier?"
for this we have to discount the "disease case" so now we have 3 possibilities instead of 4
from the picture you see that only 2 cases can be carrier and one would be a normal case
finally we add it up = 2 carrier/3 total cases = 2/3
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| Musuq
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the Zn fingers are a feature of TF for Steroid receptors and Peroxisome proliferator activated receptors (PPRAs)
Zn fingers...
memorize this table
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| vamsi2004
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thanx musuq..
goodluck.
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