DrVirgo
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38. A 68-year-old man has heterozygous familial hypercholesterolemia. Which of the following agents will decrease plasma VLDL and LDL concentrations but will cause cutaneous vasodilation that subsides with repeated doses?
A ) Niacin
B ) Nitric oxide
C ) Prostacyclin (PGI2)
D ) Prostaglandin E2
E ) Substance P
F ) Thyroxine (T4)
G ) Vasoactive intestinal polypeptide
H ) Vitamin B6 (pyridoxine)
(explain your answer)
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| reet
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A.. nician--- side effect FACIAL FLUSHING, PRURITIS
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| doc179
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A?
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| DrVirgo
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Yes, Niacin causes flush, but does it subside with repeated doses??? (didn't know that)!
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| DrVirgo
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I guess the other answers don't make sense, so its Niacin.
Anyone else?
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| robin082006
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no idea about the reason
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| DrVirgo
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But everyone agree with Niacin then?
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| robin082006
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no ans is as best as Niacin
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| DrVirgo
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ok. I agree robin.
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| mjl1717
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since i sense the ambiguity Ill state niacin. sometimes ASA is given for side effects!!!!!!
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| druas
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you r right mlj...
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| ureterpolyp
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Niacin, but I don't know why they will put this so obvious"cutaneous vasodilation that subsides with repeated doses"
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| mjl1717
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dont we usually build some tolerance to most meds?
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