DrVirgo
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19. A 23-year-old woman with a history of asthma comes to the physician's office because she has had progressive wheezing over the past 2 days. Which of the following drugs is most likely to induce bronchodilation in this patient by activation of adenylyl cyclase?
A ) Albuterol
B ) Beclomethasone dipropionate
C ) Cromolyn sodium
D ) Ipratropium bromide
E ) Theophylline[font=Arial][/font ]
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| reet
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theophyline.???.. - phosphodiesterase inhibiter ,,,inccrse cAMP...SO activation of adenyl cyclase---
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| doc179
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A ?
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| msyamp
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its A. reetu!! increase in cAMP how does it stimulate adenylcyclase yaar. it is the product of the enzyme.right? it may even inhibit because of accumilation of product.
remeber this yaar.pneumonic is
Gq - ip3 DAG >>> q
Gi - inh of cAMP >>>i
Gs - stimulation of cAMP >>> s
a1 a2 b1 b2 qiss (kiss)
M1 M2 M3 qiq (kick)
D1D2 si (sigh)
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| mjl1717
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the beta agonist-a
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| msyamp
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hey reetu!! how does inc c AMP cause activation of adenylcyclase. it is its product not dubstrate. it will actually inhibit.
remeber this pneumonic.
Gq >> IP3 DAG >> ca+ >> q
Gi >> inh cAMP >> i
Gs >> stimulate cAMP >> s
a1 a2 b1 b2 qiss (kiss)
M1M2M3 qiq (kick)
D1D2 si (sigh)
so its "kiss kik si"
hope you got it. all the best
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| DrVirgo
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I agree.
Good mnemonic msyamp... I also remember it somewhat like that. 
(also to add: H1 is Q and H2 is S) -not sure how to remember that.
Anyway, I also think its: A. Albuterol
Albuterol is a beta 2 agonist. It acts on Gs which stimulates AC and thus breaks down ATP to cAMP, then cAMP activates PKA....
msyamp... can you explain what happens after that.... how do we get to bronchodilation from this point? (i'm stuck). Thanks.
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| Cedrick
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Asthma .-Albuterol
Choice A
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| Diego Casali
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A
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| waqastariq
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albuteral babay
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| vamsi2004
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to be true,, i dint understand the mnemonic posted by msyamp. how to interpret it?
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| docarchana
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excellent mnemonic. thanku msyamp
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