vinaysaini19
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Lehninger means muscle glycogen. Because mm. lack glc-6-phosphatase so it cannot produce glucose for blood. Hence the sole purpose of storing glycogen in mm. is to provide it with source of energy during intense activity.
M. glycogen is for exclusive use by muscle only.
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| nadiabarati
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Lehninger say: resting muscles use free fatty acids and keton bodies, mild active muscle use glucose but in intense activity the speed of blood circulation is not enough for the demands so muscle use its glycogen stores anerobically and produce lactate and energy
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| coolmavs
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Actually the muscle using free fatty acids and ketone bodies at rest as energy source! Hmmm....intersesting! Didnt pay attention to this previously for sure!
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| coolmavs
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Actually if somebody could clarify, the use of FFA or Ketone bodies as the primary source of fuel is in the Fasting state...not in the fed state?
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| krsna
Forum Senior
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yup i totally agree with u coolmavs...muscle uses glucose during fed state and rest...in the fasting state fatty acids and ketones.wat they were saying above might have been in a resting muscle in fasting state...
hope im not too confused on this.
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| mazinger
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Well guys I think you should be aware, which types of fibers you are talking about and what do you mean by resting state... Type 1, slow twitch, have mitochondria (stain red), use glucose, fatty acids, ketone bodies.. In fact glucose can only be taken from the blood in the insulin world.. While in the glucagon world it uses mainly fatty acids and ketone bodies.. Type 1 fibers are fibers have a low tendency to fatigue and can remain contracted for long periods of times no wonder why they are abundant in postural muscles.. Type 2, Fast twitch, dont have mitochondria (are white), CAN ONLY MAKE anaerobic glycolysis, these fibers are responsible for intense muscle contractions, have a high tendency to fatigue, use glycogen as fuel and make lactic acid, no wonder why our muscles ache after an intense work out (specially when you are at the very first days of your training).. Now I have a question for you guys.. Denervation atrophy which fibers are mainly affected? Disuse atrophy what type of fibers are affected? Upper motor neuron atrophy what type? and last Lower motor neuron also... make conclusions from what I said... U can make it
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| drk1980
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good Qs mazinger!
here is an attempt, denervation...red and white. Disuse....white. UMN....red and LMN....both.
plz correct all of them 
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| mazinger
Forum Guru
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Upper motor neuron white and the reason is these dudes have spastic paralysis and are hypertonic (muscle tone is given by red fibers) and LWM is right 3 out of 4 drk1980.. way to go..
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| enthu
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nice concept mazinger..but I could not understand why in UMN the white fibres will atrophy..u said that tone is by red fibres...and in UMN its spastic paaralysis so how did u conclude that it will be the white fibres that will atrophy..thanks for the wonderful explaintion u already gave.
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| mazinger
Forum Guru
Topics: 46
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Well its easy, UMN muscles are hypertonic, muscle tone is provided by type 1 red fibers, so these fibers are still active, while type 2 are incative and then atrophy.. Remember in order for muscle fibers remain normal they need a constant stimulus otherwise thet atrophy..
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| hollmann
Forum Newbie
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fat cells ....the last sourse???
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