6. Which of the following best describes how Clostridium perfringens evades destruction by neutrophils in patients with clostridial myonecrosis? A) Damaging neutrophil membranes by means of a membrane-damaging toxin B) Preventing contact with neutrophils by means of a polysaccharide capsule C) Preventing phagocytosis by disruption of neutrophil actin polymerization D) Survival in the cytoplasm of a neutrophil E) Survival in the phagosome of a macrophage
please explain it!
Ashley84 Forum Newbie
Topics: 2 Posts: 19
02/08/06 - 01:37 PM  
 
   
 
  #2
Answer A.
The most important factor of virulence of C.perfrigens is alpha toxin, that is a phospholipase that causes alteration in membrane homeostasis