drk1980
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Which of the modifications of an endogenous active peptide can slow the clearance?
A. administering the peptide with an enteric coating
B. Decreasing amino acid number
C. Ensuring a free amino group at the N terminus
D. Ensuring a free carboxyl group at the C terminus
E. substituting a D for an L amino acid
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| reet
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| anjushree
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i think it to be E
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| reet
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yeah,, i would go fr E.. too
may be chemical specificity ..is different.
Edited by reet on 02/02/06 - 12:14 PM
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| drk1980
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dunno if this makes sense.....wud ' Ensuring a free carboxyl group at the C terminus ' repel(likes repel) it from filtering thru the neg charged basement memb of the glomerulus hence slowing clearance???
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| skyhigh
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that's what i think too, d, b/c more neg charge, less clearance.
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