drk1980
Forum Guru
Topics: 147
Posts: 1,038
|
In a normal healthy state, which is the predominant immunoglobulin type in serum?
|
| skyhigh
Forum Guru
Topics: 105
Posts: 561
|
IgG
|
| drk1980
Forum Guru
Topics: 147
Posts: 1,038
|
good,...which subtype?
|
| skyhigh
Forum Guru
Topics: 105
Posts: 561
|
there are many,
i am guessing IgG1
|
| drk1980
Forum Guru
Topics: 147
Posts: 1,038
|
superb guess!......out of the four subclasses of IgG, which one cannot bind to C1q to activate classic complement?
|
| sturge_weber
Forum Guru
Topics: 77
Posts: 1,042
|
well i couldnt resist adding this
in q bank, they said, igg1 is the most common type.. and it is hence not considered a subtype of igg class, whereas the othrers re considered the subtypes of igg class...
and we often have the igg2 or igg3 deficiency, but never the igg4 deficiency
and igg2 deficiency is often associated with iga deficiency, hence dont give blood products to them containing iga, or else anaphylactic reaction
this q was once posted by u drk about iga def with igg2...
|
| skyhigh
Forum Guru
Topics: 105
Posts: 561
|
IgG2?
|
| drk1980
Forum Guru
Topics: 147
Posts: 1,038
|
thanks for the input. i hadnt known before this tht IgG1 is not considered a subclass of IgG!
About the deficiencies...well, tht ws to be my next Q! 
I reckon from Kaplan that we hv do hv G4 deficiencies but just not isolated....in combination with one of the others.......for the sake of comparison, like Hepatitis D!
(did i already post smthng on ths?? my memory must be fading out  )
|
| drk1980
Forum Guru
Topics: 147
Posts: 1,038
|
actually the answer to the last Q is IgG4.
Do u know which is the most common IgG subisotype deficiency in adults?
|
| skyhigh
Forum Guru
Topics: 105
Posts: 561
|
assuming IgG2
|
| drk1980
Forum Guru
Topics: 147
Posts: 1,038
|
oh that wud hv been an excellent assumption if the Q was, which is the most frequent IgGsubtype deficiency in children
Its IgG3 def in adults most commonly.
Name the cytokine(s) involved in class switch to IgG.
|
| sturge_weber
Forum Guru
Topics: 77
Posts: 1,042
|
so u mean to say that the most common igg is igg3 in adults, and igg4 in children........................??????
|
| skyhigh
Forum Guru
Topics: 105
Posts: 561
|
IL-2?
|
| drk1980
Forum Guru
Topics: 147
Posts: 1,038
|
sturge, most frequently seen def in children from the IgGsubtypes is IgG2 (the answer guessed by skyhigh)
skyhigh, iam not too sure of the intricacies of the interleukin world(who knows IL-2 might hv ths role tht is not yet known). but Kaplan mentions some other IL. try again...
|
| skyhigh
Forum Guru
Topics: 105
Posts: 561
|
I THINK IL-4 helps to class switch to IgG and IgA
|
| drk1980
Forum Guru
Topics: 147
Posts: 1,038
|
yes IL-4 in class switch to IgG and IgE
|
| reet
Forum Fanatic
Topics: 152
Posts: 1,411
|
so igg1 is most common type...  in adults or in children,,??
as u guys said... igg2-in children,igg3 in adults.
___________________
Live as u were to die tommorow. Learn as if u were to live forever.
|
|
| |
| | | | | | | | | | | | | | | | | |
