reet
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.4 yr girl, 5/7 h/o fever, abdo pain, nausea, vomitting , diarrhoea. Skin has petechiae. Hepatospleenomegaly. Hb-8.7, plts 60,000. Bld smear-fragmented RBC. Whcih renal finding most likely?
a. Glomerular crescents
b.IgG GBM Ab
c.Membranoproliferative GN
d.Narrowing of capillary wall by fibrin deposition
e.Periglomerular grannuloma with giant cells
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| reet
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| | 01/24/06 - 12:24 PM
1 of 1 forum leaders found this post helpful
| #2 |
2 nbme que
2children can mount diverse antibody to different thousands of antigens. Which DNA mechanism?
1)recombination
2)amplification
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| reet
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3 .ques
which chain in the fetal Hb is reposible for higher affinity for Oxygen?
A.alpha chains
B.beta chains
C.gamma chains
D.alpha & beta
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| drk1980
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the first case has all findings of H-S purpura.....the histo pic i think is Narrowing of capillary wall by fibrin deposition. similar Q in kap sim.
the second Q...maybe its recombination..
Correction: first case is HUS
Edited by drk1980 on 01/24/06 - 01:19 PM
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| reet
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4 ques
Tolerance od Bcell to self Ag develops in which compartment?
a.Lymph node
b.spleen
c.bone marrow
d.thymus
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| drk1980
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gamma chains for the third one...since fetal Hb has higher affinity and tht is alpha2gamma2.
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| drk1980
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4th Q....iam thinking bonemarrow. plz correct me if its wrong.
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| reet
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q5) Nonate with ambigious genitalia....enlarged clitoris and a single perianal opening anterior to the anus. No masses are palpable in the labio scortal pouches or the inguinal canal......what is the cause?
1. Androgen insensitivity Syndrome
2. 21 hydrooxylase deficiency
3. Mixed gonadal dysgenesis
4. 5 alpha reductase deficiency
5.True hermophodites
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| reet
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q6
A 22 yr old woman is evaluated because of recurrent sinopulmonary infection and diarrhea. Her IgG conc. is within the reference range. Which is the following immunodifficiency.....
1. AIDS
2.Ch. granulomatous disease
3.Common variable immunodifficiency
4. DiGeorge
5. Isolated IgA def.
6. SCID
7.WIskott- Aldrich
8.X linkes aggamaglobulinemia
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| reet
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q 7
which overthe counter drug taken foe pain causes constipation and mild urinary problems?
1.ibuprofen
2.aspirin
3.diphenhydramine
4.gauienfesin
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Q8
Eight hundred motor vehicle collisions occurred over 2 years in a city with a population of 600,000; 600 of these accidents were alcohol related. During the same period, there were 400 fatalities due motor vehicle collisions, of which 75% were alcohol-related. Which of the following best represents the 1-year incidence of alcohol-related motor vehicle fatalities in this community?
A. Unable to determine from available information
B. 600 per 600,000
C. 450 per 600,000
D. 300 per 600,000
E. 150 per 600,000
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| reet
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q 9
INTIAL PHASE TYPE1 COLLAGEN SYNTHESIS BY:
CHONDROBLAST
CHONDROCYTE
OSTEOBLAST,,, OSTEOCYTE
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| reet
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q 10
WHEN POLIOVIRUS PASSED THRO SERIES OF CELL CULTURE IT LOSES ITS NEURO VIRULENCE,THE VIRUS IS:
1.INACTIVATED
2.ATTENUATED
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| Doc2378
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1. D its Hemolytic Uremic $
2. Recombination
3. Gamma Chains
4. Bone Marrow
5. 21-hydroxylase def
6. Isolated IgA
7.?
8. 300 per 600,000
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| reet
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doc ,, can u exaplin ques 8??
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| reet
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and this question
62-yr man, 6-month of strange behavior. No focal neurological signs, but prominent grasp and snout reflexes.
A. Arteriosclerosis
B. Dementia, Alzhermer type
C. Huntington’s Dz
D. Normal aging
E. Pick’s dz
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| drk1980
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Q 7 maybe diphenhydramine...Mblocking activity symptoms.
Q 10 inactivated
last one before this post....picks disease....frontal lobe damage signs.
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| reet
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explain questions 2,5,8,10 pleeeeeeeese.
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| drk1980
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Q 10 Passing thru serial cell cultures to lose neurovirulence....tht is ATTENUATED. Used in Live oral sabin polio vaccine.
Inactivated is by culturing the virus in tissue and inactivating it with formalin. Stringent tests are carried out to ensure complete inactivation. This is used as Killed injectable Salk vaccine.
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| drk1980
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Q8 A..unable to determine from info. Coz stats r gvn for a 2 year period and Q asks incidence over 1 year.
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| skyhigh
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is 9 osteoblast,osteocyte
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| reet
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i think --- OSTEOCYTE.
CUZ OSTEOCYE,,AND FIBROBLAST are the two intiate tpy 1 collagen syntheis
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| reet
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how u would describe ques 2?
recombination
amplification
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| skyhigh
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i'll try
amplification means making MANY COPIES of the same type of antibody.
Recombination means that antibody has genetically different conformations that are each specific for diff. antigens.
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| drk1980
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reet, i googled this..."Collagen type I is laid down by bone forming cells (osteoblasts) in organised parallel sheets (lamellae) and subsequently the collagen chains become cross-linked by specialised covalent bonds (pyridinium cross-links) which help to give bone its tensile strength."
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