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Author9 Posts
  #1

does it affect cytp450?

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  #2

i don't think so...

anybody else?


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  #3

na , me too dont think so

  #4

Look at this site:

http://medicine.iupui.edu/flockhart/table.htm

  #5

so it is?

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  #6

it seems like it is an inducer of P450

and it also listed as one of the substrates for P450 metabolism.

  #7

kaplan q bank says its not while in my notes on first aid I have written it as a p450 inhibitor..I think I am wrong.

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  #8

irreversibly inhibits H/K ATPase in the stomach parietal cell. Cyt P450 functions in the liver, I don't think is an effect of omeprazole.

  #9

G&G says, it inhibits some of the isozymes of cytochrome P450, yet it does'nt cause major drug interactions however toxicity of few drugs have been reported to be exacerbated when co-administered with PPI's.

wel, there are so many drugs which has gotta do a thing or two with cytochromes, but try to remember the important ones....


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