DrVirgo
Forum Hero
Topics: 1084
Posts: 3,472
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What causes TD?
Is the following correct:?
Neuroleptics (which decrease dopamine) cause Tardive Dyskinesias (tongue protrusion, tremors and spasms of body). I have read that TDs are Parkinson like Effects (which makes sense because both neuroleptics and parkinsons have decreased dopamine in common.
In Kaplan Behav. its written "Anti-Parkinson drugs aggravate TD"
I was wondering why this is because Anti-Parkinson drugs increase dopamine, whereas Neuroleptics decrease dopamine, so how can they both be responsible for the same side effects?
Even if you give Anti-muscarinics for Parkinsons, this decreases Ach; what does this have to do with TD?
Please explain. Very confused.
Thanks.
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| ed222
Forum Senior
Topics: 4
Posts: 147
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Dr.Virgo I explained this in the pharm forum.
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