anjushree
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MOA--bactericidal,req b lactum ring
bind to PBP-dec cross linking of peptidoglycans
activating of autocatylatic enz
RESISTANCE----b -lactamase
change in PBP
Change in porin structure
PnG---FOR syphilis
nafcilin,methacillin,oxacillin----suspected staph
ampicillin----listeria,e-coli
amoxycillin----H.pylori
pipercillin,ticarcillin---pseudomonas
ALL are eliminated by kidney,except nafcillin,oxacillin---eliminated in bile
S/E---hypersensitivity,
naf-neutropenia
meth-interstitial nephritis
add more info
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| mjl1717
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seizures are possible with poor renal function,
pennicillinase resistant --methicillin, nafcillin, oxacillin, dicloxacillin, cloxacillin
methicillin can cause interstitial nephritis and granulocytopenia
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| anjushree
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seizure with imipenem
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| anjushree
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name carbapenem which do not req ciliastatin
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| mjl1717
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dont know,thats "relatively new" info
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| anjushree
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MEROPENEM
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| mjl1717
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THANK YOU, BUT how many different carbapenams do you count.?
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| anjushree
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i know only 2--imipenem& meropenem
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| anjushree
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Topics: 64
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ampicillin ,,amoxicillin-----use in e.coli,proteus inf
in H.influenza,morxella catarrhalis
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