malinda Forum Guru
Topics: 162 Posts: 654
| | 01/15/06 - 10:25 AM  
 
   
 
|   #1 |
The clearance of several substances was measured at a constant glomerular filtration rate and constant urine flow rate, but at increasing plasma concentrations of the substance. Under these conditions, clearance will increase at high plasma concentrations for which of the following substances? A. Creatinine B. Mannitol C. Penicillin D. Phosphate E. Urea plz explain why u choose what i choose.
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| drk1980 Forum Guru

Topics: 147 Posts: 1,038
| | 01/15/06 - 10:37 AM  
 
   
 
|   #2 |
the mechanism of Tm reabsorption described in the Q is the same used by glucose as well as sodium, aminoacids, ketone bodies, protiens & peptides and Even Phosphate. IMO, the Q is just testing if you know that list. anyone else?
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| skyhigh Forum Guru
Topics: 105 Posts: 561
| | 01/15/06 - 10:44 AM  
 
   
 
|   #3 |
so urea is ans? urea is reabsorbed at collecting duct right? and the rest mentioned above are reabsorbed at the PCT does this include mannitol and creatinine Plz correct me.
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| malinda Forum Guru
Topics: 162 Posts: 654
| | 01/15/06 - 10:49 AM  
 
   
 
|   #4 |
is it related to all substances transported by fasciliated diffusion which will show Tm?
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| sturge_weber Forum Guru
Topics: 77 Posts: 1,042
| | 01/15/06 - 10:56 AM  
 
   
 
|   #5 |
i think phosphate is the ans
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| msyamp Forum Fanatic
Topics: 60 Posts: 1,462
| | 01/15/06 - 11:00 AM  
 
   
 
|   #6 |
yes phosphate . please give the answer i am dubt ful about urea at this is also having a high Tm
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| drk1980 Forum Guru

Topics: 147 Posts: 1,038
| | 01/15/06 - 11:14 AM  
 
   
 
|   #7 |
sturge, ur right skyhigh, 50% of urea is reabsorbed in the PCT...and that too passively. As i recall, Distal tubule onwards it is impermeable to urea. unless ADH action is present. malinda, its related to those substances, esp the natural ones listed earlier who are reabsorbed at Tm. msyamp, are u sure urea is also absorbed by Tm?
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| malinda Forum Guru
Topics: 162 Posts: 654
| | 01/15/06 - 11:20 AM  
 
   
 
|   #8 |
yes phosphate is the right answer
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| anjushree Forum Guru
Topics: 64 Posts: 386
| | 01/15/06 - 09:29 PM  
 
   
 
|   #9 |
urea is passively reabsorb phosphate is ans
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| sturge_weber Forum Guru
Topics: 77 Posts: 1,042
| | 01/22/06 - 02:56 PM  
 
   
 
|   #10 |
well the substances reabsorbed by the tm mechanism re the glucose, peptides, proteins, aminoacids, calcium and phosphate.... urea is only partially reabsorbed by the tm and partially absorbed pssively, hence it cannot be the answer, hence the only answer choice that matches is phosphate
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