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Kaplan Qbank USMLE



Author3 Posts
  #1


Furosemide (choice A) inhibits the active reabsorption of sodium, potassium, and chloride in the thick ascending

limb. This will deplete the medullary gradient, which could result in a slightly hypotonic urine, but furosemide will

significantly increase the fractional clearance of sodium, and hence the osmolar clearance. HOW DOES MEDULLARY DRADIANT DEPLETION CAUSE HYPOTONIC URINE PLZ?


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  #2

hey boss. you your self have agreed that furosemide inh medullary na absorbtion and so depletion of gradient. that means the normal conc of urine that is to take place in loop is being obstucted.ony the acsending loop is impermiable and all other side permiable to water. so the retained na will cause osmotic sucking in of water. so.....

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  #3

thanx .I am just going through a memory and understanding block right now.lack of sleep kills.shaking head

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