JAS
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please see in the attached
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Qestion in genetics.doc (56 KB, 52 downloads)
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| drk1980
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i'll venture with D
On second thots, i'll go by A!!
Edited by drk1980 on 01/13/06 - 01:22 PM
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| msyamp
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i go with d. because duchenne's is x linked. father carrier and son got it.
drk you aregood
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| drk1980
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msyamp, but DMD is X-linked. so i ruled out D coz if that embryo is a male he cant be a 'carrier' , he'll be affected. If its a female then she wud hv got the lower band from mother and upper from dad. And the lower band of the mothers is not the mutant one....and dad doesnt hv it. So thts ruled out.
Heck the Q says mother doesnt hv the mutant dystrophin...so iam wondering who's kid it is!
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| msyamp
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ya maan same with me. i dint thnk of felony or adultration here. but i though some DMD traits that can also be transferred in x linked dominant way. yes
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| reet
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what about choice C??
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| anjushree
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i think ans is A
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| reet
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post the answer with explaination
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| JAS
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I even do not und
The correct answer is E. Duchenne muscular dystrophy<?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" />
(DMD) is an X-linked recessive disease typically affecting
only males. Females who inherit the disease-producing
gene are usually unaffected carriers. In this family, the
mother is a carrier of the DMD gene. Comparing her
RFLP pattern to her affected son shows that the top (larger)
fragment in her pattern is a surrogate marker for the
DMD gene. The lower (smaller) fragment in her pattern
is a surrogate marker for her normal allele. (Note that in
the unaffected father, genetically unrelated to the mother,
the top fragment is a marker for his normal gene.) Three
embryos will produce phenotypically unaffected children:
Embryo 1 (a female homozygous for the normal allele),
Embryo 3 (a male), and Embryo 4 (a female carrier).
Only Embryo 2 will produce a male with DMD.
Embryo 4 will produce a carrier female who is not
affected (thus eliminating choices A and C).
Embryo 3 (choice B) will produce a normal male without
the DMD allele.
Embryo 1 (choice D) will be a female carrier of the DMD
allele. Embryo 1 is homozygous for the normal allele.
erstand the answer, how can people know the sex of child. See the answer:
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| msyamp
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good one not to boast. thought of that. but i thought i was thinking a ot.
good one
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| JAS
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How can you know the sex of embryos?
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| reet
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oh okayyyy,,,i was confused about choice C- 4 embryo.. GOT UR ANSWER.
thanks jas fr posting this question.
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| reet
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X linked disease---so son will be affected... so which band matches with DAD.. I THINK SO.
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| msyamp
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sex is know by the fact that in x linked disorders. if you have two alleels it is she. if you have one allel it is he
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