msyamp
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anaphylaxix
and hemolysis. renal failure. like what exactly you want to know. it leads to somany manifeststion. multiorgan failure
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| skyhigh
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it leads to unconjugated hyperbilirubinemia and jaundice as well right.
i guess i was really trying to find out why Rh+ in child doesn't lead to jaundice, but ABO incompatibility does.
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| msyamp
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rh+ also causes it but to a less extent. and more causes renal pathos leading to hydrops
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| reet
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YOUR QUES IS--why Rh+ in child doesn't lead to jaundice, but ABO incompatibility does?
in Rh + HDN ----actually wht happen is... antibody attaches to RBC ag and splenic macrophage destroy it. so unconjugated bili relesed by macrophages. which MOTHER HANDLES.so LESS JAUNDICE BUT ITS PRESENT THERE
OKAYYY AS such abo incompatibility --preformed antibodies formed which causes extravascular hemolysis...--Leads to unconjugated bilirubinemia
PLZ CORRECT ME... i just guessed it all
Edited by reet on 01/10/06 - 06:39 PM
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| msyamp
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great going you got it. its not a guess . its an educated guess.
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| Geroo
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I think there is jundice in both ABO and Rh incompatibility
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| reet
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but lil difference there according to skyhigh question
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| hihopes
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according to goljan rapid review:
abo incompatibility is less severe (if fact protective against) than rh incompatibility. both have anemia and jaudice at birth (with 24hrs) as a result of extravascular hemolysis and both have anemia (less severe in abo) There is also an increased risk of kernicterus in rh incompatibility. Hope this helps.
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