robin082006
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A 45-year-old male complains of gradual weight gain over the past several years. His fingers have enlarged so much that he can no longer wear his wedding ring. He sweats more than usual, and in particular, his hands are constantly sweaty. He has also noticed a gradual coarsening of his facial features. An MRI reveals the presence of a 1.5-cm tumor in the anterior pituitary. Which of the following endocrine abnormalities is likely to be present?
A.  Decreased plasma growth hormone concentration
B. .gif) Decreased plasma IGF-1 concentration C
C. Decreased plasma insulin concentration
D. Impaired glucose tolerance
E. Increased suppression of growth hormone secretion with oral glucos
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| dr.gurinder
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i think it should be B.i don't know the explanation.can anyone give a detailed explanation to the above question.
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| msyamp
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it is impared glucose tolerance. it asks us that you shud diagnose acromegaly. thats is gh producing tumour. and then action of it on glucose metabolism.
decreased plasma igf-1 is not seen but the revesrs increase is seen.
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| sturge_weber
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yep its impaired glucose tolerance
gh in th body forms insulin like growth factor, and when there is atumour producing gh, it will increase the insulin like growth factor
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| sturge_weber
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yep its impaired glucose tolerance
gh in th body forms insulin like growth factor, and when there is atumour producing gh, it will increase the insulin like growth factor
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| robin082006
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you got it msyamp and weber
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