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Kaplan Qbank USMLE



Author8 Posts
  #1

Platelet count about 500,000 cells/mirco lt(Thromocytosis) is seen in:
A) hemosiderosis
B)hereditary spherocytosis
C)T.B
D)hemolytic uremic syndrome
E) none

  #2

oops spelling mistake.Its thrombocytosis.

  #3

I think Hereditary Spherocytosis after post splenectomy(but I dont think I can assume splenectomy has been done!)....... :oops:

  #4

Hi,
thanks for the answer.But here since it is not mentioned that the case of hereditary spherocytosis is post splenectomized.The best answer is T.B.

  #5

but why would platelet count increase in TB?

  #6

I read at http://www.medscape.com/viewarticle/443138_3

Chronic inflammation/Infection releases IL-6(main one responsible), IL1, TNF and other cytokines which cause the liver to produce Thrombopoeitin which acts on the CSF-Megakaryocyte (precursors) :arrow: more megakaryocytes :arrow: more platelets.

  #7

Thanks Meg, for the web-site...... grin

___________________
Gurvinder Singh
India.

  #8

Thanx Meg for the explanation.







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