asmi
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What is the normal INR(international normalized ratio) and what is its significance?
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| filiz
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The INR - international normalized ratio - is the ratio of the patient's clotting time to the lab's mean reference value - normalized by raising it to the "ISI" power -
This allows all PT's to be "corrected" to an international standard. Subsequently, a patient on warfarin would have the same INR in France as in Seattle. NOTE: the INR is designed specifically for warfarin therapy as it has been standardized only for the Vitamin K-dependent factors.
The INR, therefore, corrects for variations that would occur with different thromboplastin reagents--between different hospitals, or when a single hospital gets a new lot of reagent.
:arrow: The INR uses the ISI to equate all thromboplastins to the reference thromboplastin through the following equation:
INR = (patient PT/mean normal PT)ISI
:arrow: http://www.pathology.med.unc.edu/path/labs/test/i...
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| asmi
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Thanks alot for the answer
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| meg
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http://www.api-pt.com/pdfs/2002Binr.pdf
gives more information like how to calculate, what it normal value, significance in different conditions etc
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