tikka
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A 23-year-old male wants to increase his muscle mass by injections of anabolic steroids obtained from a "friend". Which of the following is the LEAST likely complication he will suffer from prolonged use of anabolic steroids: A Hepatocellular carcinoma B Acne C Decreased sperm count D Increased direct bilirubin E Aplastic anemia
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| Geroo
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E.aplastic anemia
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| Doc2378
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? A. Hepatocellular Carcinoma
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| sturge_weber
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is it A
as anabolic steroids can lead to hepatic adenoma but not hcc, well can someone tell about e, not sure of that too
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| msyamp
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i too think itis A.
Acne due to direct stimulation of sebum secretion.
decreased sperm count due to increased peripheral estrogen
increased dirct bilirubin due to cholestasis
aplastic anemia? can be due to inhibitory action on bone marrow??
hepatcellular ca may be the answer.
i amy be totally wrong please correct
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| Geroo
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I think in rare cases and long time use of anabolic steroids it can lead to hepatic carcinoma,but i didn't read that it leads to aplastic anemia,may be I'm wrong!!
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| sturge_weber
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http://www.sportsci.org/encyc/anabstereff/anabste...
it must be aplastic anaemia then, as this says hcc...
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| Geroo
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Good job sturge thanks
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| msyamp
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thank you sturge!!!
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| Doc2378
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Ok guys looks like this one goes t Geroo ...
Here's what I found on the net:
'AS have also been used in the treatment of refractory anaemia due to bone marrow hypoplasia, aplastic anaemia, osteoporosis and inoperable mamary carcinoma (breast cancer). '
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| robin082006
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I go with decreased sperm count. I saw this info somewhere.
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| msyamp
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no robin steroid cause decreased sperm count
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| ssrpk
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yes, by inducing the negative feedback to gonadotrophs.
good question!.
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| robin082006
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sorry, I didn't see the word "LEAST", So I go with E
Hope that I'll have no mistake like this in the future.
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