mjl1717
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Briefly why would an entity that blocks alpha 1 receptors cause orthostatic hypotension??
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| drk1980
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alpha agonists hv a vasoconstrictive tone on the peripheral vessels....arterioles and capacitance veins...a block of this action results in pooling of blood in the veins on postural change. esp severe in elderly. tht correct?
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| mjl1717
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Normally the baroreceptor reflex prevents the pooling of blood. Alpha 2 antagonist block this reflex which causes vasoconstriction and increase H.R.
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| robin082006
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I watched Kaplan Video and it said that any drugs that dilate veins may cause orthostatic hypotension.
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