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Kaplan Qbank USMLE



Author5 Posts
  #1

<?xml:namespace prefix = st1 ns = "urn:schemas-microsoft-com:office:smarttags" />Tay sach's dis, an autosomal recessieve disease caused by a deficienc of Hexosaminidase a, is lethal in childhood. In a population of Ashkenazi Jews, blood testing shows the frequency of heterozygotes to be 0.1. what is the probabilty that the first child of two individuals from this population with no family history of the disease will have Tay sachs????
a.0.25
b.0.11
c.0.0625
d.0.0025
e. Cannot be calculated from the information given<?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" />


  #2

D?

Since 2pq= 1/10

therefore probability of mating of 2 heterozygotes from the population = 2pq x 2pq= 1/100

Probability of aa from an Aa x Aa cross= 1/4

Combined probability = 1/4 x 1/100 = .0025


Edited by Doc2378 on 12/24/05 - 08:55 PM

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  #3

yes answer is D.


  #4

yes answer is D 1/400 that is 0.0025

  #5

good job friends..







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