fictiondurden
Forum Junior
Topics: 19
Posts: 20
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Why does suppression of all osteoblast activity not guarantee that the person will experience increased net deposition? Also, what does it mean for one hormone to have a "permissive effect" on the action of another hormone?
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| mildus
Forum Guru
Topics: 19
Posts: 614
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Permissive effect:
e.g. ACTH and aldosteron. ACTH doesn't increase aldosterone secretion but it is only a trophic factor which must be present in order to aldosterone synthesis take place.
Iodids have permissive effect on thyreoid hormons, which means there can be no regullar thyroid hormons synthesis without them.
There are also hormons which have a permissive effect on growth,which means they don't increase growth by themselves, but they are important for growth. I think thyroid hormons are with such effect.
This is my opinion, if I have made a mistake, please let me know
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| sturge_weber
Forum Guru
Topics: 77
Posts: 1,042
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thats what i think
osteoblasts work with osteoclasts to exert their effect
the il 1 receptors present on the osteoclasts re activated, which activate receptors on the osteoblasts, hence the bone deposition or bone resorption cant occur alone, they occur with both receptors togethet
permissive effect i agree with mildus
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| reet
Forum Fanatic
Topics: 152
Posts: 1,411
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ALSO CORTISOL released in stress,is permissive fr GLUCAGON in hypoglycemia.
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