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demnat
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Topics: 6
Posts: 35

11/28/05 - 06:35 PM 1 of 1 forum leaders found this post helpful

Can someone explain what is LFA-1 and what we have to know about in easy way????

reet
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Topics: 152
Posts: 1,411

11/29/05 - 12:07 PM

LFA--leucocyte function associated antigen-1

Source of LFA-1 (CD11/CD18) is LEUKOCYTES...

LFA-1 are adhesion molecules..bind neutrophils,monocytes and lymphocytes to VASCULAR ENDOTHELIUM with help of (via ICAM .)

ICAM ,VCAM are also adhesion molecules ,their source is ENDOTHELIAL cells.

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dariush
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Topics: 20
Posts: 356

12/27/05 - 09:50 AM

i just wanted to add that it is an INTEGRIN (a class of adhesion molecules) that binds I-CAM-1,2,3

do not mix it with LFA-3 that is a CAM itself (an Ig CAM)!!

Edited by dariush on 12/29/05 - 06:32 AM

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