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Author5 Posts
  #1

An 18-year-old man is brought to the emergency department by friends after he passed out and became unarousable. He has no history of medical problems. There is alcohol on his breath and no evidence of trauma. His blood pressure is 110/60 mm Hg, pulse is 70/min, and respirations are 6/min. The lungs are clear to auscultation. There is a normal S1 and S2. A grade 2/6, systolic ejection murmur is heard. The liver edge and spleen tip are not palpable. Test of the stool for occult blood is negative. Neurologic examination is difficult to assess. Reflexes are 1+ bilaterally. All extremities respond to painful stimuli. His blood alcohol level is 200 mg/dL; toxicology screening is also positive for benzodiazepines in the blood andcocaine metabolites in the urine. The patient does not respond to infusion with naloxone, glucose, or vitamin B1 (thiamine). Abuse of which of the following substances is the most likely cause of these findings?

(A) Alcohol only

(B) Alcohol and benzodiazepines

(C) Alcohol and cocaine

(D) Alcohol and PCP

(E) Alcohol and salicylates


Edited by frontal on 11/25/05 - 08:48 AM

  #2

Shit. I'm sorry about the terrible way the post has appeared. I most certainly didn't type those 'lefts'.mad

  #3

Okay, I just discovered the 'edit' option and deleted all the 'lefts'. Please explain your answer if possible.

  #4

B) Alcohol and benzodiazepines
naloxone opioid antidote
glucose, or vitamin B1 (thiamine)----alcohol

Alcohol and Benzodiazepine cause RS depression

So the drug to be given is
flumazenil which is a benzodiazepine antidote for the treatment.



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  #5

Answer:B.

Keep it up, ARJ. Thank you for the explanation.








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