karamazov
Forum Newbie
Topics: 12
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pathophysiologic explanation and its RX ???
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| Doc2378
Forum Guru
Topics: 46
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Its a Side effect seen with nigrostriatal DA blockade..and is characterised by hyperpyrexia, catatonia, rigidity. It is thought to involve excessive release of Ca2+...(much like malignant hyperthermia seen with anesthetics)...
Rx: symptomatic, Dantrolene, Bromocriptine
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| karamazov
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| chemamr
Moderator and PGY1
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it can cause also agitation instead of catatonia. But itīs more common the latter.
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