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Kaplan Qbank USMLE



Author3 Posts
  #1

Related to gluconeogenesis please select the best answer.

A- Pyruvate & Krebs cycle intermediates in the gluconeogenesis process transform mitochondrial oxaloacetate ----- malate to across the inner mitochondrial membrane.

B- Oxaloacetate from pyruvate & citric acid intermediate pathway is catalyzed by mitochondrial PEP carboxykinase.

C- Fructose 1-6 bisphosphatase & glucose 6 phosphatase reactions are exergonics & bidirectionals.

D- Von Gierke's desease is caused by the lack of glucose 6-phosphatase in the muscle.

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  #2

A is right, B is wrong because that named process is located in cytosol, not in mitochondria, C is wrong because these reactions with named enzymes are one-way, the opposite reactions require another enzymes, D is wrong because that ilnees happens because of deficiency of the enzyme in liver and kidney, not muscles.

  #3

you got it

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