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Kaplan Qbank USMLE



Author6 Posts
  #1

which of the following is true of cytokines?

A-Transforming groth factor-B enhances B cellproliferation and suppresses secretion of inflammation mediators

B-TNF-alpha is secreted by macrophages.

C-Interferon -B has antiviral activity and inhibits MHC Class 1 expression.

D-TNF-Bis secreted by bone marrow stromal cells.

E-TNF stimulate T cell proliferation

___________________
Ruben sssss

  #2

What's up guy? is too easy or is too hard, come on .

___________________
Ruben sssss

  #3

B

  #4

TNF possess many of the same activity as IL-1. TNF differs from IL-1 in that TNF are not able to stimulate T cell proliferation and IL-1 has only limited ability to lysis tumor cells.
TNF- alpha secreted by macrophages when estimulated by antigen.TNF- alpha is associated with production of hemorragic necrosis tumors.
--TNF Betha is produce by T cells and B cells. TNF betha is responsible for killing tumor cells and virally infected cells.
--Interferon Betha inhibits synthesis of viral protein by triggering the host cell to produce a second protein that interferes with the viral protein synthesis, Interferon Betha is primarily secreted by fibroblast and epithelial cells and enhances MHC class 1 expresion.
TGF- betha inhibits T and B cell proliferation. TGF-betha is chemotactic for monocytes and induces secretion of inflammatory mediators.

___________________
Ruben sssss

  #5

answer is E

  #6

The answer is B
I give the explanation in my second E-mail.

___________________
Ruben sssss







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