karusmle
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which one of the following drugs does not produce central anticholinergic syndrome:
1. atropine sulphate
2.glycopyrolate
3.antihistaminics
4.tricyclic antidepressants
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| Geroo
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glycopyrolate?
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| ujaala
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anti histamines ?
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| cyra
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It is glycopyrrolate...it has a quarternary structure and cannot cross the BBB.
Edited by cyra on 11/07/05 - 12:07 PM
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| Geroo
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anti histamins has central M blocking activity,while glycopyrolate has only peripheral anti cholinergic activity it doesn't enter CNS.correct me if i'm wrong,,,
Edited by Geroo on 11/07/05 - 02:16 PM
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| ujaala
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yes ur rite... iptratropium and glycopyrrolate has no CNA entry..
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| ujaala
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yes ur rite... iptratropium and glycopyrrolate has no CNS entry..
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| dariush
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2.glycopyrolate
a quarternary amine, can be given PO and doesnt cross BBB
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| karusmle
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right answer is glycopyrolate
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