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Kaplan Qbank USMLE



Author5 Posts
  #1

Hi,

Why is Cu essential for heme synthesis. Where is it a co-factor?

thanks


  #2

I dont know if it is essential (where did you read that?) but copper is a cofactor of ferroxidase that converts ferrous to ferric iron for binding transferin.


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  #3

Thank you. I read that in the Princeton book I'm busy with. They just said it is essential.

  #4

pyridoxine B6 is needed in heme synthesis too

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  #5

B6 is a cofactor of ALA synthase which is an enzyme catalyzing rate-limiting reaction in heme synthesis







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